This is the beginning of countless sci-fi stories. According to the TV and movies I've seen, this will lead to customizing fetuses, mostly for intelligence, and then the question becomes does society accept those people as their leaders (Brave New World) or criminalize their gene-enhanced intellect (Star Trek: Deep Space Nine)?
this post was submitted on 19 Jun 2025
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Black Mirror episode
As I recall, the reason the Federation outlawed genetic manipulation is due to what happened with the Eugenics Wars, the details of which are murky due to temporal interference, but one of the root causes was clear. While the end results of genetic engineering (Khan Noonien-Singh and his Augments) were undoubtedly superior to normal humans in every way, they also incredibly aggressive and arrogant, a flaw their creators could not correct, as the science was still in its infancy. One of the scientists remarked that "Superior ability breeds superior ambition".
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checks correlation of education to voting outcomes
Checks news
It will be seen as an anti-control danger and banned entirely by the nearly single-circle Venn diagram of government officials, oligarchs, and religious figures.
They will be quiet about the true nature of their decision. Instead, it will be called a danger to society, ungodly, and unnatural. Rumors will be started that it creates autistic psychopaths, and that anyone in any country that touches the technology will need to be permanently ostracized.
Or enforce social hierarchies based on genetic traits? (Gattaca)
I was thinking red rising, but that sounds similar. Hadn't heard about this, gotta watch this, thanks :D
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Humanity, one step closer to get rid of all of the genetic defects that we have accumulated because of our own reproductive stupidity.
I wish for a future in which genetic diseases do not exist. 👐
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This seems good initially.
I just really really hope they won't try to "cure autism" with this next.
Autism is an important and fundamental part of me. The fact that it's often classified as a disease is understandable, but nevertheless sickens me.
I don't want them to "cure autism" by erasing it, either. I'd rather they try to "cure autism" by improving on what it can help a human be capable of doing. That way, if we have a real-life "Butlerian Jihad" like from the lore of Dune, we have Mentats (human computers) to replace "thinking machines"(AI and computers).
Don't worry. Autism is more complicated.
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Holy crap. The obvious use for this would be in vitro. However, I cannot wait to see how this affects those already born. Could it be used on someone who is a 7 year old to rid them of this? What if they're 50? So cool. Can't wait to see where this goes.
And in the US, religious assholes want to ban IVF for exactly this reason, because it's "playing God".
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Could it be used on someone who is a 7 year old to rid them of this?
No. Gene editing works in this case since they're just working with a few cells. But a whole human is way more cells. Not only that, but the cells have already developed into structures that are much harder to access, and difficult to change. Any gene therapy may only affect a few cells.
On top of that, there's also a bunch of ethical issues around altering a human when they've already formed, and we don't really know if it would be possible to do so, or if it would make things worse.
Until someone who knows more tells me otherwise, no. It would have to be applied to a human at the stage of a single cell
You are right (at the 8 cell stage you can still separate them and treat them one at a time, giving you multiple shots at IVF)
Two of the main issues regarding gene editing when not talking single cells are the transfer into the nucleus, and then accessing the DNA you want.
In bacteria, the DNA kinda just swims around in the cell, which makes editing easy if you can get the CRISPR/Cas9 complex in the cell. But animal cells have another membrane surrounding the DNA, making the transfer less than straightforward.
Regarding access: our DNA isn't lying around like mom's spaghetti, but rather pretty tightly packed around histones - a protein octamer.
This means that your target might not be reachable (the cell itself has 3 options iirc: slide the DNA over the surface of the histone, replace a part of the histone with an alternative, or remove the histone altogether) Since the way the DNA is wound around the histones affects gene activity (something tightly packed is not active, something in a loose area is getting transcribed into mRNA and therefore possibly active), you cannot just unwind all of it.
The only time this is not the case is during cell division, where the nucleus is getting dismantled so the DNA can be duplicated and both new cells can get their own copy. But many cells do not divide in an adult (except for a reservoir of stem cells which are there to replace lost cells)
So, it's all very complicated.
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i can't tell if you're serious.
Hard to say at this point. This early testing was on cells in a petri dish. It will take a lot of study to convert this to a treatment on living humans and determine the best time to intervene.
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