I'd have to go with the wood grain Atari 2600, I'm a sucker for 70's designed electronics.
While I definitely agree the overall best design goes to the Atari 2600, this comes in close second for me:
This bad boy (or girl, rather) is the Casio Loopy. Yes, Casio, the company primarily known for making wristwatches. This console was only released in Japan, and when it launched it had a target demographic of girls and young women. The console came with a built-in sticker printer, and the games were woman-targeted games in genres like romance, fashion, and life simulation (like Animal Crossing). Only 10 games were ever made for the Loopy, by the way. Its biggest failure and reason for not selling well was being a console that had games that looked like the SNES but having to directly compete with the PS1 and N64, as well as the replaceable sticker cartridges being very expensive.
Now, I am a man, and I am clearly not a part of the target demographic of this console. The games are entirely uninteresting to me, except maybe the Animal Crossing-like game "I Want A Room In Loopy Town." But something about the curved shape of the console and its cool purple hue speak to me. The black cover for the sticker ejection port has me imagining a newer version playing an animated logo on that part if a small screen was behind it. The absurdly massive Eject button just looks like it gives the most satisfying "kerchunk" when you press it to eject a cartridge.
In third place I'd have to give a shout out to the Apple iMac G3, even though I really dislike Apple products and its neither a game console.or made for gaming in general, something about the white and bold color combo just looks really cool. The mouse was really bad though. Got a bit of that Frutiger Aero look.
