As far as I know, there are still rad hardened 486 chips being made for satellite applications. But my info may be a few years out of date.
The 486DX was the last cpu I truly understood (i did things like disassemble code for it). After the pentium instructions were added, I kind of stopped tracking changes to instruction sets. Now I'd be lucky to follow someone else's assembly with the help of tools. It was a good time for me, back in the day.