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genotype rarity: ⭐⭐⭐⭐⭐ (pawb.social)

submitted 4 days ago* (last edited 4 days ago) by [email protected] to c/[email protected]

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"A Novel Sex Chromosome Mosaicism 45,X/45,Y/46,XY/46,YY/47,XYY Causing Ambiguous Genitalia"

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[–] [email protected] 12 points 4 days ago (1 children)

I think it's not, since the X chromosome contains vital genes while the Y chromosome kinda does nothing. If you don't have an X chromosome, you should be missing important genes. I might be wrong though.

[–] [email protected] 3 points 4 days ago (1 children)

I heard about XYY, XXY and even XXX so was wondering about this one. Since it's still 50/50 (more or less) and it has to contain at least one X, I would guess. Still confused by the article title though.

[–] [email protected] 24 points 4 days ago (1 children)

YY is not possible in isolation because you need at least an X chromosome to survive as stated above, however! this article is about someone with extreme mosaicism, meaning that some of his cells don't have the same chromosomes as the rest of his body, so some of his cells are YY but other parts of his body have X chromosomes so it's still survivable overall

[–] [email protected] 6 points 4 days ago (1 children)

Wow, so kinda like chimerism? Though this is on another level. Couldn't find a wiki page but definitely would like to read about it. By the way, while searching for this, I found about XXYY which I also didn't know about.

[–] [email protected] 4 points 4 days ago

Monotremes possess 5X and Ys, but their system is more related to birds and reptiles ZW,