this post was submitted on 30 Jun 2025
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I understand it’s being misused by people who don’t need it, particularly in the entertainment industry. But I’m almost 400 lbs and my eating is worse than it’s ever been and I’m just in desperate need to rid myself of this obsession with always eating more no matter what. Does anyone here have any experience with it? I’ve heard it just works by making you nauseous but I’ve read elsewhere that that’s just a common side effect. At this point I’m nauseous most of the time anyway.

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[–] [email protected] 0 points 1 day ago* (last edited 1 day ago)

I had a colleague tell me that GLP-1s inhibit individual fat cell (adipocyte) growth, but can ultimately lead to adipocyte proliferation, especially if lifestyle modifications aren't made, and that this is a major factor in rebound weight gain. Can't speak to the veracity myself and am having trouble interpreting the literature off-hand.