this post was submitted on 19 Jun 2025
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[–] [email protected] 57 points 1 week ago (4 children)

I did not realize CRISPR was so powerful as to remove chromosomes entirely. Can CRISPR be used to change someone's genetic sex? Republicans would freak out.

[–] [email protected] 1 points 1 week ago (1 children)

CRISPR on our gonads to produce estrogen instead of testosterone?

πŸ€” It's pretty tempting, and as long as it's not hereditary, I'm all up for it. πŸ³οΈβ€βš§οΈ

[–] [email protected] 1 points 1 week ago

Or testosterone instead of estrogen. Though I'm doubtful that exchanging X and Y chromosomes will change the physiological function of your existing organs that much.

I honestly just meant to do this for no other reasons than to flip the bird to conservatives who arbitrarily define sex chromosomally.

[–] [email protected] 31 points 1 week ago

RED ALERT! WOKE LIBERAL COMMUNISTS ARE USING CRISPR BEAMS FROM LOW IRBITING SATTELITES TO FORCIBLY CHANGE OUR GENDERS! BUY MY ANTI-WOKE SUPPLIMENTS TO PROTECT YOUR MANLINESS.

[–] [email protected] 9 points 1 week ago (2 children)

I'm fully expecting in our lifetimes for CRISPR to be able to flip the genome or whatever in the body that produces sex hormones such that testes and ovaries could swap functions and produce the opposite sex hormone.

Between this and using your own DNA to apply to scaffolding to grow an organ, the future is bright. I also expect to see sex organs of the opposite sex grown in a lab from your own DNA and then transplanted into you, and the body wouldn't reject them.

[–] [email protected] 8 points 1 week ago (1 children)

I also expect to see sex organs of the opposite sex grown in a lab from your own DNA and then…

I’m kinda glad that didn’t go where I thought it was gonna go but you know it will.

[–] [email protected] 3 points 1 week ago

it's basically just masturbation.

[–] [email protected] 7 points 1 week ago

The latter technology exists, but nobody seems to be interested in expanding it past this pilot.

[–] [email protected] 13 points 1 week ago (1 children)

By my limited understanding that might be feasible right now in utero, which obviously is not exactly what we want.

I think that maybe in the future we could change someone's sex when they're older. Honestly I think it's maybe just the matter of research on this not being focused on genetic changes after the womb.

[–] [email protected] 6 points 1 week ago (1 children)

The article was not clear about what stage in someone's life the CRISPR treatment can be applied. I would have assumed early in gestation. But this raises questions such as how down syndrome would be detected at that stage. If in vitro is the method, then why not simply filter out down syndrome at that stage?

[–] [email protected] 2 points 1 week ago* (last edited 1 week ago)

People are already doing that. But if it can be removed instead then you could increase the viable number of embryos for IVF and decrease how many rounds you have to go through. Edit: not to mention that sometimes the baby is naturally conceived and then if this issue is found during testing, it means you have to choose whether or not to abort and start over. Being able to use CRISPR at that point reduces abortions.