Yeah, I've had my number reported as spam before from someone impersonating my number, and I've run into several customers through work whose numbers had been reported as spam as well. I've also gotten calls from people who supposedly missed a call from me, that I had never called before. Most likely they missed a spam call that was impersonating my number.
Thankfully it wasn't too hard to get off of the spam call registries, and you can even preemptively register your number with them as a non-spam number to try to avoid getting caught in this. But it's still frustrating to have to deal with this at all, and it's far too difficult to realize your phone number has been flagged as spam. The people you frequently talk to probably have you added as a contact and will never get a chance to see you've been flagged as spam. And if you call anyone new, they probably won't answer your call because it shows up as spam. End result is you just have trouble getting in touch with people you haven't already swapped contacts with, and never get a good chance to learn why.