I'm calling it now:
Eventually these streamers are going to run out of runway, and they're already placing the blame on piracy. They're going to start pushing for more intense legal action against piracy and self-hosted options. Likely they'll push for broader enforcement of copyright and criminal charges, but i think they'll also litigate against plex and other self-hosted software and services as enabling/dealing in pirated content. Worst-case is that they start placing restrictions on VPN's and proxies, and they'll maybe couch it in a 'concern for national security'. FOSS has been having a moment the last couple years, but I'm very nervous about the attention their attracting.
I'm not sure what this will look like, but Netflix and others have already started putting out foreboding OP eds and statements addressing the market impact of pirating, and the digital media market sector is simply too big for legislators to ignore. The more companies like Disney and Netflix take on losses, the more pressure will be placed on legislators to act.