https://en.wikipedia.org/wiki/XX_male_syndrome

tldr biology is dice rolls and humans are intersex for no reason sometimes

on a side note one of my friends had this and she only found out when she started transitioning. she is now a trans woman with XX chromosomes. i can only imagine how fucking vindicating it must have felt

https://static.scientificamerican.com/sciam/assets/File/Pitch_sketch_final.png?w=2000

This is the best resource I've seen to show things relatively simply.

The TL;DR is that a whole "Y" chromosome isn't exactly responsible for "maleness", the SRY gene is. It's normally on the Y chromosome, but mutations can occur placing that gene onto the X chromosome. Inversely, someone could inherit a Y chromosome without that gene, in which case they would develop with female traits.

It's not considered trans because someone with 46XX plus the SRY gene would develop male genitalia, be identified as male at birth, and likely identify themselves as male. For some types of these conditions, there are plenty of people walking around with no clue that their chromosomes don't match their gender.

Disclaimer: I'm not a geneticist, so i could have explained something a little off.

De La Chappell syndrome, congenital adrenal hyperplasia, androgen exposure in utero, ovotesticular disorder of of sex development all result in a person with cis male characteristics and in some cases cis male typical genitalia despite having xx chromosomes

I googled it for you.

https://en.wikipedia.org/wiki/XX_male_syndrome

In 90 percent of these individuals, the syndrome is caused by the Y chromosome's SRY gene, which triggers male reproductive development, being atypically included in the crossing over of genetic information that takes place between the pseudoautosomal regions of the X and Y chromosomes during meiosis in the father.[2][7] When the X with the SRY gene combines with a normal X from the mother during fertilization, the result is an XX genetic male. Less common are SRY-negative individuals, those who are genetically females, which can be caused by a mutation in an autosomal or X chromosomal gene.[2] The masculinization of XX males is variable.

You've heard of xy people and xx people, but wait till you hear about X people!

Or xxx people, or xxy people, or... dies

Outward, their genitals might look like those of the oposite sex.

Gene expression is not as straightforward as people think. All sorts of weird shit can happen, and that's not even including gene mutations.

Maybe she means the exceptions?

Exceptions: While XX and XY are the most common sex chromosome combinations, there are exceptions, such as individuals with variations in their sex chromosomes, such as XXY (Klinefelter syndrome) or XYY.

The impression of legitimacy enjoyed by chiropractic is too damn high. I was well into my 20s before I ever heard a single word about it being pseudoscience. Walking around (usually on people's fucking spines) calling themselves doctors, I absolutely believed it was just some sub-variety of physiotherapy, which I guess is the point. In the whole universe of alternative medicine, I think that has to be the practice which has most effectively disguised itself as conventional medicine. It's gross.

It may as well be astrophysics for some people.

Art has weight that influences the human psyche. Let the man work.

It be an art.