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I look at that and I'm not sure that's right either. Maybe if you took concentrated nicotine extract (pure) and drank it, then yeah, it could become lethal.

I don't think anyone can smoke enough cigarettes or vape enough to reach a dangerous toxicity level. I'm pretty sure you'd pass out long before reaching a fatal dose. So the only way you could get to that point is to either inject, ingest or otherwise absorb a lot of nicotine all at once. The usual delivery methods (via the lungs) would probably not work for this. I suppose if you rigged up a continual tobacco burner and hot boxed an area with smoke containing nicotine (either vapor or smoke from burning it), maybe? Or if you slapped on a few dozen nicotine patches after smoking a few packs and went to bed?

The only other way I can think of to get that much nicotine in you is to buy high concentration vape liquid and drink it; but I'm pretty sure your body would simply vomit it back out and you'd survive. I'm sure it wouldn't be pleasant, but it wouldn't be fatal.

Cocaine on the other hand.... I don't know enough about, but I'm sure people have OD'd on it, so I'm sure there are ways.

It's very likely.

Everything radioactive is incredibly dangerous.

I work with WiFi professionally, so I have a pretty good understanding of radio waves from that. On top of that, I'm a radio hobbyist, so I gathered a pretty good understanding of electromagnetic waves and how they operate... Mainly in the context of getting them from A to B successfully, but the physics behind it does not change regardless of frequency.

While all radio waves can dissipate as heat when absorbed by an object, the wavelength of that signal affects how small of an object it will interact with. Lead is a good example, since it's a dense lattice of atoms and can interact with most electrical and magnetic fields. Radio waves have a hard time penetrating even a small layer of lead because they're usually too large of a wave to fit between the atoms. At a certain, very high, frequency, lead gets less effective, and only by making that lead layer thicker and thicker, basically putting the randomness of atom arrangement in the path of the wave, can the signal be stopped.

When a high frequency wave interacts with flesh, like a person, it will usually penetrate a distance then be absorbed into the material, this is the basic principle that allows x-ray imaging to work. The more dense the material (bones vs muscle and organs and such), the more is absorbed, and you get a dark spot on the resulting image. I won't get into the development of the images, because they're usually inverted, that's a function of photography and how pictures work.

Taken to the extreme, higher and higher frequency signals, like uranium produces, goes even further, interacting with the atoms that make up your DNA, and destroying them. It's a gruesome process and it takes a long time before the symptoms of radiation appear, and a very long recovery (or death) in most cases. With uranium, you'd die from radiation long before the toxicity of the uranium can kill you, even if you're "only" taking .

Knowing as much as I do, radiation at this level is scary. It's silent, with no visible indication that it's happening, and it will kill you dead without any indication it ever existed. It always humors me when people take up arms against some new wireless technology where the principle frequency is under 100Ghz, and people are so afraid of it giving them cancer. The lightbulbs in your house are more apt to give you cancer than 5G or whatever. Light is an electromagnetic wave, the same as the radios in the 5G towers, but light is in the terahertz range, over 500x higher frequency than your wifi. Above that, in terms of frequency is UV-A, UV-B, etc, up to x-rays, and on. Above x-ray, is all the radioactive emissions from uranium, plutonium, etc. Literally thousands of times higher frequency than the evil 5G. EM only becomes ionizing (aka, dangerous) around UV-B, which is why you should always wear sunscreen.

We (humans) only use higher frequency EM in the context of medical use (cancer treatments, x-rays, etc) in highly controlled environments, and for use in power plants and bombs. I'm sure some industrial uses exist too, but I'll just skip over that since it usually has the same controls as medical uses. The only other place I know of that we use radioactive material at all is in smoke detectors. We limit it, we regulate it, we keep the stupid public away from it, because they don't know the danger of such substances.

Sorry for the rant, but yeah. Holy shit.

I'm pretty sure the figure for heroin is on the high side too. Most people won't have a tolerance, and a lethal dose would be quite a bit lower than this.

Fuckin A, I only drink the good shit.

More than 1200 mg of pure THC, or 1200mg of cannabis leaves?

Those aren't even remotely the same thing, in the same way that 12oz of beer and 12oz of everclear are very different, or 1g of pure nicotine is very different than 1g of tobacco leaves.

Not to mention, LD50 is about a single dose. There's a big difference between taking one shot an hour for 16 hours straight, and chugging 16 shots in one go.

This is per kilogram of your mass. So if your weight is 80kg then the lethal dose would be 96000mg not 1200. At least that's how I understand this.

LD50 is specifically a dose that kills 50% of the subjects.

Lower doses can kill, just less than 50% of people.

Good point, I hadn’t considered it was based on body weight, and rather thought it was just median population