tedu

joined 9 months ago
[–] [email protected] 24 points 5 months ago (1 children)

We're all trying to figure out where these headlines came from. The stable channel with all the fixes does not (at this time) bundle the warning. How is that users have become confused and believe the dev channel is the only way to get security fixes?

[–] [email protected] 2 points 5 months ago

I don't know why you'd jump to the dev channel, though. Just apply the stable channel update.

[–] [email protected] 97 points 5 months ago (18 children)

I'm going to go way out on a limb here and guess nothing will happen if I do neither.

[–] [email protected] -5 points 5 months ago

Thoughts and prayers for scarjo.

[–] [email protected] -3 points 5 months ago (2 children)

People are concerned about non issues all the time.

[–] [email protected] 8 points 5 months ago (1 children)

Should have gone with Barclay as Kovitch.

[–] [email protected] 6 points 5 months ago

I'm sure it still works in photoshop or whatever, just not the windows stuff.

[–] [email protected] 2 points 5 months ago

Because it comes from a laptop with rounded corners on the top of the lid and a flat hinge on the bottom.

[–] [email protected] 23 points 5 months ago (8 children)

What critical information are people putting in the six missing pixels?

[–] [email protected] 35 points 5 months ago (2 children)

Now people want recall?

[–] [email protected] 27 points 5 months ago (6 children)

It's so weird.

Due to the fact that Facebook has chosen to involve software that will allow the theft of my personal information, I do declare the following: on this day, 30th November 2014, in response to the new Facebook guidelines and under articles L.111, 112 and 113 of the code of intellectual property, I declare that my rights are attached to all my personal data, drawings, paintings, photos, texts etc... published on my profile since the day I opened my account. For commercial use of the foregoing my written consent is required at all times. Those reading this text can copy it and paste it on their Facebook wall. This will allow them to place themselves under the protection of copyright. By this release, I tell Facebook that it is strictly forbidden to disclose, copy, distribute, broadcast, or to take any other action against me on the basis of this profile and/or its contents. The actions mentioned above apply equally to employees, students, agents and/or other staff under the direction of Facebook. The contents of my profile include private information. The violation of my privacy is punished by the law (UCC 1 1-308 - 308 1 -103 and the Rome Statute). Facebook is now an open capital entity. All members are invited to post a notice of this kind, or if you prefer, you can copy and paste this version. If you have not published this statement at least once, you will tacitly allow the use of elements such as your photos as well as the information contained in your profile update. Do not share. Just copy on paste on your wall.

1
DIY Espresso (www.fourbardesign.com)
 

High pressure, high forces, long lever arms...all of that meant heavy and strong (read: expensive) parts which I was not looking forward to having to fabricate. Instead, I settled on the simpler idea of harnessing the power of compressed gas. Instead of using a high mechanical advantage lever to push a piston, compressed CO2 would be dispensed from a small and inexpensive 12g or 16g cartridge which would then generate the requisite pressure to properly extract espresso. This concept is not actually novel; both an unsuccessful kickstarter and a now-defunct handheld espresso maker (with a fanatical user base) employed this mechanism.

 

Espresso coffee is among the most consumed beverages in the world. Recent studies report a protective activity of the coffee beverage against neurodegenerative disorders such as Alzheimer′s disease. Alzheimer′s disease belongs to a group of disorders, called tauopathies, which are characterized by the intraneuronal accumulation of the microtubule-associated protein tau in fibrillar aggregates. In this work, we characterized by NMR the molecular composition of the espresso coffee extract and identified its main components. We then demonstrated with in vitro and in cell experiments that the whole coffee extract, caffeine, and genistein have biological properties in preventing aggregation, condensation, and seeding activity of the repeat region of tau. We also identified a set of coffee compounds capable of binding to preformed tau fibrils. These results add insights into the neuroprotective potential of espresso coffee and suggest candidate molecular scaffolds for designing therapies targeting monomeric or fibrillized forms of tau.

In vitro results, take with a grain of salt or shot of espresso.

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