The creator of these comics is a Christian, with the message of them being a Christian message/allegory.
The message here is that if you disconnect yourself from God and try to live independent from God, you lose your purpose and/or are helpless to fulfill your "true purpose" (which, to a Christian, "true purpose" = serving/following God).
That said: I'd strongly suggest that people stop posting these comics and giving this guy attention. They're meant for Christians and are not really relevant to people outside of that.
EDIT: I made a (regrettable) visit to the website to satisfy my curiosity and found the title & description:
Absolute Freedom – God (in control of all things) gives us freedom to choose what to do, but we don't get to choose the outcome.
Make of that what you will.