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COVID symptoms seem to never touch certain people — and researchers may have finally figured out why (www.cbsnews.com)

submitted 1 year ago* (last edited 1 year ago) by [email protected] to c/[email protected]

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Here is the study the article references:

https://www.nature.com/articles/s41586-023-06331-x

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[–] [email protected] 1 points 1 year ago

Saved you a click:

A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection

We observed that individuals carrying this common allele (approximately 10% in individuals with European ancestry) are more than twice as likely to remain asymptomatic after SARS-CoV-2 infection compared with those who do not, and a notable effect of HLA-B*15:01 homozygosity increasing the chance of remaining asymptomatic by more than eight times.

Together, our results strongly support the hypothesis that HLA-B*15:01 mediates asymptomatic COVID-19 disease through pre-existing T cell immunity due to previous exposure to HKU1-CoV and OC43-CoV.