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2024-11-11

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Scientists Pinpoint Main Cause of Sensory Hypersensitivity in Autism (scitechdaily.com)

submitted 5 months ago by [email protected] to c/[email protected]

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This study has identified the anterior cingulate cortex (ACC) as a key area in the brain responsible for sensory hypersensitivity in autism spectrum disorders. Utilizing a mouse model with a Grin2b gene mutation, heightened neural activity and connectivity in the ACC was observed. Suppressing this hyperactivity normalized the sensory hypersensitivity, offering new insights into treatment options

https://www.nature.com/articles/s41380-024-02572-y (open access)

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[–] [email protected] 1 points 5 months ago (1 children)

anterior cingulate cortex (ACC)

This is where sensoric processing happens in the limbic system, right?

[–] [email protected] 2 points 5 months ago

ACC is mainly studied for its role in cognition and emotion. In the article linked it's mentioned >The ACC is one of the higher-order cortical regions that have been extensively studied for cognitive and emotional brain functions, but have been understudied for brain disease-related sensory abnormalities.> I also found another article on the role of ACC in cognition and emotion: https://neuro.psychiatryonline.org/doi/full/10.1176/jnp.23.2.jnp121

Also you can go through the Wikipedia article: https://en.m.wikipedia.org/wiki/Anterior_cingulate_cortex