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Osimertinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that binds to certain mutant forms of EGFR (T790M, L858R, and exon 19 deletion) that predominate in non-small cell lung cancer (NSCLC) tumours following treatment with first-line EGFR-TKIs². It exhibits a nine-fold greater affinity for select EGFR-sensitizing and T790M-resistance mutations than to wild-type EGFR¹.

(1) . https://bing.com/search?q=osimertinib+mechanism+of+action. (2) DRUG NAME: Osimertinib - BC Cancer. http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Osimertinib_monograph.pdf. (3) Mechanism of Action – TAGRISSO® (osimertinib). https://www.tagrissohcp.com/moa.html. (4) Osimertinib: Uses, Interactions, Mechanism of Action | DrugBank Online. https://go.drugbank.com/drugs/DB09330. (5) Mechanisms of osimertinib resistance and emerging treatment ... - PubMed. https://pubmed.ncbi.nlm.nih.gov/32693293/.

The article talks about the possibility of creating artificial wombs capable of supporting humans across the full nine months of development. It also mentions that even if scientists are able to overcome the scientific hurdles and create artificial wombs capable of supporting humans across the full nine months of development, society might reject them. It also discusses how artificial wombs will alter the relationship between men, women, and fetuses such that reproduction is effectively ‘degendered’.

In England you sometimes see these "wavy" brick fences. And curious as it may seem, this shape uses FEWER bricks than a straight wall. A straight wall needs at least two layers of bricks to make is sturdy, but the wavy wall is fine thanks to the arch support provided by the waves.