What about Bazzite? It comes with tons of stuff for gaming out of the box including tools to install and manage emulators and roms.
Linux Gaming
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Lakka is the official Linux distribution of RetroArch and libretro. It's built on LibreELEC.
It could be (pretty much) any distro you want -- considering scripts like armbian-gaming exists and can give you a "one stop shop" experience.
Why running scripts like these instead of downloading the "real thing"? When you have "obscure"/unsupported sbcs and you need to "make your own" version of it.
As far as I know RetroPie also has x64 images.