I think reading comprehension is far more complicated than any one method can encompass. This might help some people but hurt others. For me, it would be a distraction to try and focus on other aspects like a word. However, if you asked me about the word later, it would stand out in my mind regardless. When I was much younger, I wouldn't have understood why you might be asking me to find a word like this. I lacked the self awareness to understand how differently I perceive the world through abstraction and how others comprehend on a different level.
Personally, I tend to read slowly, but I naturally have unusually high comprehension. If I am constrained to some isolated idea prior to reading, that idea may limit my abstracting conceptualization and oversimplify my comprehension... but I'm an outlier.