Currently, the only projects I'd refer to as (remotely) GA are ChimeraOS, Endless OS, Fedora Atomic, Guix System, NixOS and their derivatives. The rest is, unfortunately, simply not there yet. The closest to these would be openSUSE Aeon. But, if you'd like FDE on your device, then you'd have to forego it for now. Currently, I would advice against relying on any other projects; including Arkane Linux, AshOS, blendOS, carbonOS, MocaccinoOS, Nitrux, openSUSE Kalpa, rlxos and Vanilla OS. Unless, you're fine dealing with whatever random and fringe issues you may have to face.
As for the previously mentioned GA 'immutable' distros, you don't like to pursue Fedora Atomic, NixOS and their derivatives for IMO fair reasons. ChimeraOS is primarily an OOTB console experience distro (aka couch gaming) that happens to be 'immutable'. Therefore, bending it (to become your distro for general use) will definitely be an involved process. But, it's possible. Likewise, Endless OS is somewhat locked down (beyond what you'd expect from your average 'immutable' distro) and has to be bend (at least slightly) in order for it to be more suitable as a daily driver.
This leaves us with Guix System. IMO, if you want to pursue this right now, then Guix System is simply the only remaining way of going forward. It's fit to suit whatever needs you'd have and offers access to official documentation that's at least a decade ahead of the one found for NixOS. However, don't expect this to be entirely painless; 'immutable' distros require (in general) a bit more know-how compared to traditional distros. And within the 'immutable distros', Guix System and NixOS are uniquely positioned for how 'powerful' they feel compare to (literally) any other distro. But, with great power comes great responsibility. Hence, you should definitely know your shit.
Finally, if FDE is not a hard requirement for you and if you can live with GNOME and if don't have qualms against containerizing everything and if you don't intend to tinker, then you might also consider openSUSE Aeon.