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this is a topic i've been heavily involved with because i still consider myself to be someone who prefers using technology at a very beginner friendly level, plus it's very good when a linux operating system makes you feel right at home when it has a modern desktop environment. this is why i really like gnome, its simplicity and usability is something available for everyone, for beginners and for a lot of other people, but if you had to, say, rearrange xfce or kde for someone who was an elderly person or an absolute beginner so that they wouldn't have any trouble using linux, how would you do it? (screenshot is my current linux mint desktop, very simple and extremely user friendly!!!!)
Those newfangled immutable distros might benefit them, since they're unlikely to want to or care about modification, and it's extra security.
Set up the web browser with a strong ad-blocker, maybe whitelisting YouTube since non-techy people are unlikely to know what to do if youtube throws up a stink about the adblocker.
Set up auto-updates maybe. For safety and such.
Otherwise make sure it looks like a dead ringer for whatever they are already used to (usually Windows) -- Same background, icons in the same places and looking similar if not the same, panels set up the same way, etc. -- This is easier with Cinnamon or KDE Plasma. Gnome... Even if you like it, it's too different, yanno? Unless they're coming from Mac, and even then it's not the same.
P.S.: Lovely background of a gay bird prince. <3