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The International Science Council appoints 100 new Fellows to help advance its vision of science as a global public good

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https://council.science/current/blog/isc-appoints-100-new-fellows/?utm_source=rss&utm_medium=rss&utm_campaign=isc-appoints-100-new-fellows

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Global Science Leaders ISC and IAP Issue Joint Statement on Protecting the Autonomy of National Academies of Science

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https://council.science/current/news/joint-isc-iap-statement-academies/?utm_source=rss&utm_medium=rss&utm_campaign=joint-isc-iap-statement-academies

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Fostering tomorrow’s science: the ISC’s engagements with Early and Mid-Career Researchers in 2023

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https://council.science/current/blog/isc-engagements-emcr-2023/?utm_source=rss&utm_medium=rss&utm_campaign=isc-engagements-emcr-2023

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The number of retractions issued for research articles in 2023 has passed 10,000 — smashing annual records — as publishers struggle to clean up a slew of sham papers and peer-review fraud. Among large research-producing nations, Saudi Arabia, Pakistan, Russia and China have the highest retraction rates over the past two decades, a Nature analysis has found.

The bulk of 2023’s retractions were from journals owned by Hindawi, a London-based subsidiary of the publisher Wiley (see ‘A bumper year for retractions’). So far this year, Hindawi journals have pulled more than 8,000 articles, citing factors such as “concerns that the peer review process has been compromised” and “systematic manipulation of the publication and peer-review process”, after investigations prompted by internal editors and by research-integrity sleuths who raised questions about incoherent text and irrelevant references in thousands of papers.

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A landmark study led by a King's academic has shown that severe asthma can be controlled using biologic therapies, without the addition of regular high-dose inhaled steroids which can have significant side effects.

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The electric eel is the biggest power-making creature on Earth. It can release up to 860 volts, which is enough to run a machine. In a recent study, a research group from Nagoya University in Japan found electric eels can release enough electricity to genetically modify small fish larvae. They published their findings in PeerJ - Life and Environment.

The researchers' findings add to what we know about electroporation, a gene delivery technique. Electroporation uses an electric field to create temporary pores in the cell membrane. This lets molecules, like DNA or proteins, enter the target cell.

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A technology developed at ETH Zurich over the past few years for controlling microvehicles using ultrasound also works in the brain, as researchers have now been able to show.

These microvehicles are gas bubbles, which are harmless and dissolve once their job is done.

In the future, these microvehicles could be equipped with medications and deliver them to specific points in the brain. This may increase the efficacy of the drugs and reduce their side effects.

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Scientists reveal unprecedented insights into human limb development, including the many intricate processes that govern their formation.

Human fingers and toes do not grow outward; instead, they form from within a larger foundational bud, as intervening cells recede to reveal the digits beneath. This is among many processes captured for the first time as scientists unveil a spatial cell atlas of the entire developing human limb, resolved in space and time.

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Researchers have established a first potential therapeutic target for a type of early-onset dementia.

Scientists have identified abnormal aggregates of a protein called TAF15 in the brains of individuals with early-onset dementia, known as frontotemporal dementia, where the cause was not previously known.

Most neurodegenerative diseases, including dementias, involve proteins aggregating into filaments called amyloids. In most of these diseases, researchers have identified the proteins that aggregate, allowing them to target these proteins for diagnostic tests and treatments.

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